Zetasizer Pro
Malvern panalytical
High performance, versatile and robust
The new Zetasizer Pro is your go-to instrument to measure a wide range of sample types and concentrations. It offers wide dynamic concentration capability and high sensitivity due to the Non-Invasive Back Scatter (NIBS) optical design.
Advantages
Even novice users will produce the highest-quality measurements using the Zetasizer Pro, which benefits from:
- Dynamic Light Scattering (DLS), which measures particle and molecule size, from 0.3 nm to 10 µm
- Electrophoretic Light Scattering (ELS), which measures the zeta potential of particles and molecules, indicating sample stability and/or propensity to aggregate
- Non-Invasive Back Scatter (NIBS), optics for versatile, high sensitivity, particle and molecular size measurements and molecular weight measurements
- M3-PALS with Constant Current Mode, for zeta potential and electrophoretic mobility measurements
- ZS Xplorer software suite, for simple and flexible method set-up and data analysis
- Adaptive Correlation, for faster, more reproducible sizing measurements with less sample preparation
- Deep learning-based data quality system, for assessment of any size data quality issues, with clear advice on how to improve results
- Optical filter wheel with fluorescence filter, to allow measurement of fluorescent samples without impairing overall system sensitivity. Also includes polarization filters for DDLS measurements
Description
Specification
Applications
Resources
The Adaptive Correlation feature enhances sample throughput by reducing measurement duration and providing greater sample knowledge. The deep learning-based data quality system gives you the confidence to know your data is the best it can be.
The optical filter wheel allows measurement of fluorescent samples without impacting overall instrument sensitivity.
Particle size and molecular size
| Measurement principle | Non-Invasive Back Scatter (NIBS) Dynamic Light Scattering |
|---|---|
| Measurement angle | 173°, 13° |
| Measurement range | Diameter: 0.3 nm – 10 μm |
| Minimum sample volume | 12 μL |
| Concentration range | Minimum sample concentration: Blue Label: 0.2 mg/mL 15 kDa Protein Red Label: 0.1 mg/mL 15 kDa Protein Maximum sample concentration: (3) 40% w/v |
Zeta potential
| Measurement principle | Mixed-Mode Measurement phase analysis light scattering (M3-PALS) |
|---|---|
| Size range | Diameter: 3.8 nm – 100 μm (2) |
| Minimum sample volume | 20 μL (4) |
| Concentration range | Red Label: 1 mg/mL (5) to 40% w/v (6) Blue Label: 10 mg/mL (5) to 40% w/v (6) |
| Sample conductivity range | Maximum: 260 mS/cm |
Static Light Scattering (molecular weight)
| Molecular weight range | 980 Da – 20 MDa |
|---|---|
| Measurement principle | Static Light Scattering with Debye Plot |
| Accuracy | +/- 10% typical |
System
| Detector | Avalanche Photodiode |
|---|---|
| Laser safety | He-Ne (633 nm) Blue label: 4 mW Max Red label: 10 mW Max |
| Temperature control range | 0°C – 120°C (7) |
| Dimensions (W, D, H) | 322 mm x 565 mm x 245 mm |
| Weight | 19 kg |
| Power | AC 100-240 V, 50-60 Hz, 4.0 A |
| Power consumption | Max 100 W, Typical 45 W |
| Ambient conditions | +10°C to +35°C, 35 to 80% RH (Non-condensing) |
| Interface | USB 2.0 or higher |
- Academia
- Bioscience
- Food and drink
- Nanomaterials
- Paints, inks and coatings
- Pharmaceuticals
